Eltrombopag inhibits the proliferation of Ewing sarcoma cells via iron chelation and impaired DNA replication

Abstract Background The treatment of Ewing sarcoma, an aggressive bone and soft tissue sarcoma, is associated with suboptimal outcomes and significant side-effects. Consequently, there is an urgent need to identify novel therapies that will improve outcomes for children and adults with Ewing sarcoma...

Full description

Bibliographic Details
Main Authors: Torin Waters, Kelli L. Goss, Stacia L. Koppenhafer, William W. Terry, David J. Gordon
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Cancer
Subjects:
Online Access:https://doi.org/10.1186/s12885-020-07668-6