A multi-scale model for hair follicles reveals heterogeneous domains driving rapid spatiotemporal hair growth patterning
The control principles behind robust cyclic regeneration of hair follicles (HFs) remain unclear. Using multi-scale modeling, we show that coupling inhibitors and activators with physical growth of HFs is sufficient to drive periodicity and excitability of hair regeneration. Model simulations and exp...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-07-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/22772 |