The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice.

Alterations in the immune cell profile and the induction of inflammation within adipose tissue are a hallmark of obesity in mice and humans. Dual-specificity phosphatase 2 (DUSP2) is widely expressed within the immune system and plays a key role promoting immune and inflammatory responses dependent...

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Bibliographic Details
Main Authors: Graeme I Lancaster, Michael J Kraakman, Helene L Kammoun, Katherine G Langley, Emma Estevez, Ashish Banerjee, Raelene J Grumont, Mark A Febbraio, Steve Gerondakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4222916?pdf=render