In vitro dissolution study of atorvastatin binary solid dispersion

In vitro dissolution study of atorvastatin binary solid dispersion

The aim of the present study was to improve the solubility and dissolution rate of atorvastatin (ATV), a slight water-soluble drug, by solid dispersion (SD) technique using a hydrophilic carrier Poloxamer 188 (POL188). Physical mixing (PM) and solvent evaporation (SE) method were used to prepare ATV...

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Bibliographic Details
Main Authors: Rahat Jahan, Md. Saiful Islam, Ahmad Tanwir, Jakir Ahmed Chowdhury
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2013-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Atorvastatin
physical mixing
poloxamer 188
solid dispersion
solvent evaporation
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2013;volume=4;issue=1;spage=18;epage=24;aulast=Jahan

Internet

http://www.japtr.org/article.asp?issn=2231-4040;year=2013;volume=4;issue=1;spage=18;epage=24;aulast=Jahan

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