Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related DisordersSummary

Regulation of CFTR Bicarbonate Channel Activity by WNK1: Implications for Pancreatitis and CFTR-Related DisordersSummary

Backgraoud & Aims: Aberrant epithelial bicarbonate (HCO3−) secretion caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene is associated with several diseases including cystic fibrosis and pancreatitis. Dynamically regulated ion channel activity and anion sel...

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Bibliographic Details
Main Authors: Yonjung Kim, Ikhyun Jun, Dong Hoon Shin, Jihoon G. Yoon, He Piao, Jinsei Jung, Hyun Woo Park, Mary Hongying Cheng, Ivet Bahar, David C. Whitcomb, Min Goo Lee
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X19301213

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http://www.sciencedirect.com/science/article/pii/S2352345X19301213

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