Exacerbated innate host response to SARS-CoV in aged non-human primates.

The emergence of viral respiratory pathogens with pandemic potential, such as severe acute respiratory syndrome coronavirus (SARS-CoV) and influenza A H5N1, urges the need for deciphering their pathogenesis to develop new intervention strategies. SARS-CoV infection causes acute lung injury (ALI) tha...

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Bibliographic Details
Main Authors: Saskia L Smits, Anna de Lang, Judith M A van den Brand, Lonneke M Leijten, Wilfred F van IJcken, Marinus J C Eijkemans, Geert van Amerongen, Thijs Kuiken, Arno C Andeweg, Albert D M E Osterhaus, Bart L Haagmans
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-02-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20140198/?tool=EBI