The Immunology of Hormone Receptor Positive Breast Cancer

The Immunology of Hormone Receptor Positive Breast Cancer

Immune checkpoint blockade (ICB) has revolutionized the treatment of cancer patients. The main focus of ICB has been on reinvigorating the adaptive immune response, namely, activating cytotoxic T cells. ICB has demonstrated only modest benefit against advanced breast cancer, as breast tumors typical...

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Bibliographic Details
Main Authors: Jonathan Goldberg, Ricardo G. Pastorello, Tuulia Vallius, Janae Davis, Yvonne Xiaoyong Cui, Judith Agudo, Adrienne G. Waks, Tanya Keenan, Sandra S. McAllister, Sara M. Tolaney, Elizabeth A. Mittendorf, Jennifer L. Guerriero
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Immunology
Subjects:
hormone receptor (HR)
breast cancer
immunotherapy
immune exclusion
T-cell exclusion
antigen presentation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.674192/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.674192/full

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