Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury

Water treadmill training attenuates blood-spinal cord barrier disruption in rats by promoting angiogenesis and inhibiting matrix metalloproteinase-2/9 expression following spinal cord injury

Abstract Background The permeability of the blood-spinal cord barrier (BSCB) is mainly determined by junction complexes between adjacent endothelial cells (ECs), including tight junctions (TJs) and adherens junctions (AJs), which can be severely damaged after spinal cord injury (SCI). Exercise train...

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Bibliographic Details
Main Authors: Xinwang Ying, Qingfeng Xie, Shengcun Li, Xiaolan Yu, Kecheng Zhou, Jingjing Yue, Xiaolong Chen, Wenzhan Tu, Guanhu Yang, Songhe Jiang
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Fluids and Barriers of the CNS
Subjects:
Spinal cord injury
Blood-spinal cord barrier
Water treadmill training
Vascular regeneration
Matrix metalloproteinase-2/9
Online Access:https://doi.org/10.1186/s12987-020-00232-1

Internet

https://doi.org/10.1186/s12987-020-00232-1

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