Modulation of Gut Microbiome Composition and Function in Experimental Colitis Treated with Sulfasalazine

Modulation of Gut Microbiome Composition and Function in Experimental Colitis Treated with Sulfasalazine

Inflammatory bowel disease (IBD) results from alterations in intestinal flora and the immune system. Sulfasalazine (SASP) is a sulfa antimicrobial used to treat IBD in clinic for years. However, how SASP affects gut microbes and its potential functions remains unclear. To investigate the relationshi...

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Bibliographic Details
Main Authors: Haihui Zheng, Mingyi Chen, Yuan Li, Yuanyuan Wang, Lin Wei, Ziqiong Liao, Mengxia Wang, Fangli Ma, Qiongfeng Liao, Zhiyong Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Microbiology
Subjects:
gut microbiome
16S gene sequencing
metagenomics
colitis
TNBS
SASP
Online Access:http://journal.frontiersin.org/article/10.3389/fmicb.2017.01703/full

Internet

http://journal.frontiersin.org/article/10.3389/fmicb.2017.01703/full

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