Evaluation of in Vitro and in Vivo Depigmenting Activity of Raspberry Ketone from Rheum officinale

Evaluation of in Vitro and in Vivo Depigmenting Activity of Raspberry Ketone from Rheum officinale

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Melanogenesis inhibition by raspberry ketone (RK) from Rheum officinale was investigated both in vitro in cultivated murine B16 melanoma cells and in vivo in zebrafish and mice. In B16 cells, RK inhibited melanogenesis through a post-transcriptional regulation of tyrosinase gene expression, which re...

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Bibliographic Details
Main Authors: Te-Sheng Chang, Ling-Wei Chin, Hsiou-Yu Ding, Shiou-Yi Kuo, Victor Chia-Hsiang Lin, Jiumn-Yih Wu
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:International Journal of Molecular Sciences
Subjects:
B16 melanoma
tyrosinase
inhibition
zebrafish
melanogenesis
Rheum officinale
raspberry ketone
Online Access:http://www.mdpi.com/1422-0067/12/8/4819/

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http://www.mdpi.com/1422-0067/12/8/4819/

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