Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine.

Formulation, Pharmacokinetic, and Efficacy Studies of Mannosylated Self-Emulsifying Solid Dispersions of Noscapine.

PURPOSE:To formulate hydroxypropyl methylcellulose-stabilized self-emulsifying solid dispersible carriers of noscapine to enhance oral bioavailability. METHODS:Formulation of noscapine (Nos) self-emulsifying solid dispersible microparticles (SESDs) was afforded by emulsification using an optimized f...

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Bibliographic Details
Main Authors: Terrick Andey, Apurva Patel, Srujan Marepally, Mahavir Chougule, Shawn D Spencer, Arun K Rishi, Mandip Singh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4710382?pdf=render

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http://europepmc.org/articles/PMC4710382?pdf=render

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