Paradoxical Effects of Tumor Shrinkage on Long-Term Survival of Cancer Patients

In this article, we challenge the existing paradigm that greater tumor shrinkage at the end of treatment leads to longer patient survival. In particular, we identify biological conditions under which the exact opposite is true. A central role in our argument about the paradoxical effect of tumor shr...

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Bibliographic Details
Main Author: Leonid Hanin
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Applied Mathematics and Statistics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fams.2020.00027/full