The non-aggregated aggrecan in the human intervertebral disc can arise by a non-proteolytic mechanism

Analysis of both the aggregated and non-aggregated fractions of aggrecan isolated from adult human intervertebral disc using immunoblotting with antibodies specific for the different domains constituting the aggrecan core protein or atomic force microscopy revealed that many components contained the...

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Bibliographic Details
Main Authors: PJ Roughley, Y Geng, JS Mort
Format: Article
Language:English
Published: AO Research Institute Davos 2014-09-01
Series:European Cells & Materials
Subjects:
Online Access:http://www.ecmjournal.org/journal/papers/vol028/pdf/v028a10.pdf