Nonreplicating Adenoviral Vectors: Improving Tropism and Delivery of Cancer Gene Therapy

Nonreplicating Adenoviral Vectors: Improving Tropism and Delivery of Cancer Gene Therapy

Recent preclinical and clinical studies have used viral vectors in gene therapy research, especially nonreplicating adenovirus encoding strategic therapeutic genes for cancer treatment. Adenoviruses were the first DNA viruses to go into therapeutic development, mainly due to well-known biological fe...

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Bibliographic Details
Main Authors: Nayara Gusmão Tessarollo, Ana Carolina M. Domingues, Fernanda Antunes, Jean Carlos dos Santos da Luz, Otavio Augusto Rodrigues, Otto Luiz Dutra Cerqueira, Bryan E. Strauss
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
nonreplicating adenovirus vector
cancer
gene therapy
routes of delivery
virus coated with cancer cell membrane
Online Access:https://www.mdpi.com/2072-6694/13/8/1863

Internet

https://www.mdpi.com/2072-6694/13/8/1863

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