Sulforaphane Attenuates Contrast-Induced Nephropathy in Rats via Nrf2/HO-1 Pathway

Background. Oxidative stress plays an important role in the pathogenesis of contrast-induced nephropathy (CIN). The aim of this study was to investigate the antioxidant effects of sulforaphane (SFN) in a rat model of CIN and a cell model of oxidative stress in HK2 cells. Methods. Rats were randomize...

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Bibliographic Details
Main Authors: Zhihong Zhao, Guixiang Liao, Qin Zhou, Daoyuan Lv, Harry Holthfer, Hequn Zou
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/9825623