Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

Exosome-transported circRNA_0001236 enhances chondrogenesis and suppress cartilage degradation via the miR-3677-3p/Sox9 axis

Abstract Objectives Aberrations in exosomal circular RNA (circRNA) expression have been identified in various human diseases. In this study, we investigated whether exosomal circRNAs could act as competing endogenous RNAs (ceRNAs) to regulate the pathological process of osteoarthritis (OA). This stu...

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Bibliographic Details
Main Authors: Guping Mao, Yiyang Xu, Dianbo Long, Hong Sun, Hongyi Li, Ruobin Xin, Ziji Zhang, Zhiwen Li, Zhi Yang, Yan Kang
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Stem Cell Research & Therapy
Subjects:
Osteoarthritis
Exosome
circRNA
Chondrogenesis
Chondrocytes
Online Access:https://doi.org/10.1186/s13287-021-02431-5

Internet

https://doi.org/10.1186/s13287-021-02431-5

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