Performance Evaluation of SHOX2 and RASSF1A Methylation for the Aid in Diagnosis of Lung Cancer Based on the Analysis of FFPE Specimen

Performance Evaluation of SHOX2 and RASSF1A Methylation for the Aid in Diagnosis of Lung Cancer Based on the Analysis of FFPE Specimen

Emerging molecular diagnostic methods are more sensitive and objective, which can overcome the intrinsic failings of morphological diagnosis. Here, a RT-PCR-based in vitro diagnostic test kit (LungMe®) was developed and characterized to simultaneously quantify the DNA methylation of SHOX2 and RASSF1...

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Bibliographic Details
Main Authors: Juanhong Shi, Xue Chen, Long Zhang, Xia Fang, Yuting Liu, Xuyou Zhu, Haoyang Zhang, Lichao Fan, Jun Gu, Suxia Zhang, Bin She, Hongxiu Han, Xianghua Yi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
lung cancer
SHOX2
RASSF1A
DNA methylation
epigenetic field defect
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.565780/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.565780/full

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