Forging links between human mental retardation-associated CNVs and mouse gene knockout models.

Forging links between human mental retardation-associated CNVs and mouse gene knockout models.

Rare copy number variants (CNVs) are frequently associated with common neurological disorders such as mental retardation (MR; learning disability), autism, and schizophrenia. CNV screening in clinical practice is limited because pathological CNVs cannot be distinguished routinely from benign CNVs, a...

Full description

Bibliographic Details
Main Authors: Caleb Webber, Jayne Y Hehir-Kwa, Duc-Quang Nguyen, Bert B A de Vries, Joris A Veltman, Chris P Ponting
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2694283?pdf=render

Internet

http://europepmc.org/articles/PMC2694283?pdf=render

Similar Items