Immunometabolism and Sepsis: A Role for HIF?

Immunometabolism and Sepsis: A Role for HIF?

Metabolic reprogramming of innate immune cells occurs during both the hyperinflammatory and immunotolerant phases of sepsis. The hypoxia inducible factor (HIF) signaling pathway plays a vital role in regulating these metabolic changes. This review initially summarizes the HIF-driven changes in metab...

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Bibliographic Details
Main Author: Susan F. Fitzpatrick
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Molecular Biosciences
Subjects:
HIF
hypoxia inducible factor
metabolism
innate immune cells
sepsis
molecular mechanism
Online Access:https://www.frontiersin.org/article/10.3389/fmolb.2019.00085/full

Internet

https://www.frontiersin.org/article/10.3389/fmolb.2019.00085/full

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