Signaling networks converge on TORC1-SREBP activity to promote endoplasmic reticulum homeostasis.

The function and capacity of the endoplasmic reticulum (ER) is determined by multiple processes ranging from the local regulation of peptide translation, translocation, and folding, to global changes in lipid composition. ER homeostasis thus requires complex interactions amongst numerous cellular co...

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Bibliographic Details
Main Authors: Miguel Sanchez-Alvarez, Fabian Finger, Maria del Mar Arias-Garcia, Vicky Bousgouni, Patricia Pascual-Vargas, Chris Bakal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4090155?pdf=render