In Vivo Molecular MRI Imaging of Prostate Cancer by Targeting PSMA with Polypeptide-Labeled Superparamagnetic Iron Oxide Nanoparticles

In Vivo Molecular MRI Imaging of Prostate Cancer by Targeting PSMA with Polypeptide-Labeled Superparamagnetic Iron Oxide Nanoparticles

The prostate specific membrane antigen (PSMA) is broadly overexpressed on prostate cancer (PCa) cell surfaces. In this study, we report the synthesis, characterization, in vitro binding assay, and in vivo magnetic resonance imaging (MRI) evaluation of PSMA targeting superparamagnetic iron oxide nano...

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Bibliographic Details
Main Authors: Yunkai Zhu, Ying Sun, Yaqing Chen, Weiyong Liu, Jun Jiang, Wenbin Guan, Zhongyang Zhang, Yourong Duan
Format: Article
Language:English
Published: MDPI AG 2015-04-01
Series:International Journal of Molecular Sciences
Subjects:
molecular imaging
MRI
SPIONs
polypeptide
prostate neoplasms
PSMA
Online Access:http://www.mdpi.com/1422-0067/16/5/9573

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http://www.mdpi.com/1422-0067/16/5/9573

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