Quantitative evaluation of collagen crosslinks and corresponding tensile mechanical properties in mouse cervical tissue during normal pregnancy.

The changes in the mechanical integrity of the cervix during pregnancy have implications for a successful delivery. Cervical collagens are known to remodel extensively in mice with progressing gestation leading to a soft cervix at term. During this process, mature crosslinked collagens are hypothesi...

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Bibliographic Details
Main Authors: Kyoko Yoshida, Hongfeng Jiang, MiJung Kim, Joy Vink, Serge Cremers, David Paik, Ronald Wapner, Mala Mahendroo, Kristin Myers
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4232411?pdf=render