STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation

STRAP as a New Therapeutic Target for Poor Prognosis of Pancreatic Ductal Adenocarcinoma Patients Mainly Caused by TP53 Mutation

Pancreatic ductal adenocarcinoma (PDAC) has a high mortality rate and poor prognosis. KRAS, TP53, CDKN2A, and SMAD4 are driver genes of PDAC and 30–75% patients have mutations in at least two of these four genes. Herein, we analyzed the relationship between these genes and prognosis of 762 patients...

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Bibliographic Details
Main Authors: Shanshan Hu, Xiao Chen, Xiangxiang Xu, Chenlei Zheng, Wenqian Huang, Yi Zhou, Percy David Papa Akuetteh, Hongbao Yang, Keqing Shi, Bicheng Chen, Qiyu Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
pancreatic ductal adenocarcinoma
TP53
prognosis
snoRNA
STRAP
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.594224/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.594224/full

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