Modifications to the classical rat aortic ring model to allow vascular degeneration studies

Summary: The classical aortic ring model is well suited for deciphering pro-angiogenic processes. Here, we propose simple modifications of the standard protocol to study various anti-angiogenic processes from growth arrest to capillary degeneration. Aortic rings are cultured under basal conditions f...

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Bibliographic Details
Main Authors: Guillaume Blot, Thérèse-Marie Sartoris, Florian Sennlaub, Xavier Guillonneau
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166720302689