Detecting autozygosity through runs of homozygosity: A comparison of three autozygosity detection algorithms

<p>Abstract</p> <p>Background</p> <p>A central aim for studying runs of homozygosity (ROHs) in genome-wide SNP data is to detect the effects of autozygosity (stretches of the two homologous chromosomes within the same individual that are identical by descent) on phenoty...

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Bibliographic Details
Main Authors: Simonson Matthew A, Howrigan Daniel P, Keller Matthew C
Format: Article
Language:English
Published: BMC 2011-09-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/12/460