Evaluation of the impact of the proteasome inhibitor on calcium channel expression in cardiomyocytes treated with doxorubicin

One of the less known mechanisms of doxorubicin action is the effect on the functioning of the ubiquitin-proteasome degradation system (UPS). So far, the role of impaired proteasome activity in the development of anthracycline cardiomyopathy has not been clarified. It has been shown, however, that d...

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Bibliographic Details
Main Authors: Korga Agnieszka, Soroka Milena, Wicha Karolina, Humeniuk Ewelina, Adamczuk Grzegorz, Iwan Magdalena, Sysa Marcin, Dudka Jaroslaw
Format: Article
Language:English
Published: Sciendo 2018-03-01
Series:Current Issues in Pharmacy and Medical Sciences
Subjects:
Online Access:https://doi.org/10.1515/cipms-2018-0004