Evaluation of the impact of the proteasome inhibitor on calcium channel expression in cardiomyocytes treated with doxorubicin
One of the less known mechanisms of doxorubicin action is the effect on the functioning of the ubiquitin-proteasome degradation system (UPS). So far, the role of impaired proteasome activity in the development of anthracycline cardiomyopathy has not been clarified. It has been shown, however, that d...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2018-03-01
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Series: | Current Issues in Pharmacy and Medical Sciences |
Subjects: | |
Online Access: | https://doi.org/10.1515/cipms-2018-0004 |