Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study.

Maternal Smoking during Pregnancy and DNA-Methylation in Children at Age 5.5 Years: Epigenome-Wide-Analysis in the European Childhood Obesity Project (CHOP)-Study.

Mounting evidence links prenatal exposure to maternal tobacco smoking with disruption of DNA methylation (DNAm) profile in the blood of infants. However, data on the postnatal stability of such DNAm signatures in childhood, as assessed by Epigenome Wide Association Studies (EWAS), are scarce. Object...

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Bibliographic Details
Main Authors: Peter Rzehak, Richard Saffery, Eva Reischl, Marcela Covic, Simone Wahl, Veit Grote, Annick Xhonneux, Jean-Paul Langhendries, Natalia Ferre, Ricardo Closa-Monasterolo, Elvira Verduci, Enrica Riva, Piotr Socha, Dariusz Gruszfeld, Berthold Koletzko, European Childhood Obesity Trial Study group
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4865176?pdf=render

Internet

http://europepmc.org/articles/PMC4865176?pdf=render

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