The emerging molecular mechanism of m6A modulators in tumorigenesis and cancer progression

The emerging molecular mechanism of m6A modulators in tumorigenesis and cancer progression

N6-methyladenosine (m6A) is the most abundant RNA modification; m6A modifications are installed by methyltransferases, removed by demethylases and recognized by reader proteins. M6A plays crucial roles in a variety of biological processes by regulating target RNA translation, splicing, nuclear expor...

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Bibliographic Details
Main Authors: Shuiping Liu, Qiujie Li, Ke Chen, Qin Zhang, Guohua Li, Lvjia Zhuo, Bingtao Zhai, Xinbing Sui, Xiaotong Hu, Tian Xie
Format: Article
Language:English
Published: Elsevier 2020-07-01
Series:Biomedicine & Pharmacotherapy
Subjects:
M6A modification
Tumorigenesis
Cancer progression
Diagnostic biomarker
Cancer therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332220302900

Internet

http://www.sciencedirect.com/science/article/pii/S0753332220302900

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