PERK eIF2 alpha kinase is required to regulate the viability of the exocrine pancreas in mice

<p>Abstract</p> <p>Background</p> <p>Deficiency of the PERK eIF2α kinase in humans and mice results in postnatal exocrine pancreatic atrophy as well as severe growth and metabolic anomalies in other organs and tissues. To determine if the exocrine pancreatic atrophy is...

Full description

Bibliographic Details
Main Authors: Iida Kaori, Li Yulin, McGrath Barbara C, Frank Ami, Cavener Douglas R
Format: Article
Language:English
Published: BMC 2007-08-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/38