Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice

Abstract Background and aims Atherosclerotic cardiovascular disease is highly prevalent and its underlying pathogenesis involves dyslipidemia including pro-atherogenic high density lipoprotein (HDL) remodeling. Vitamins C and E have been proposed as atheroprotective agents for cardiovascular disease...

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Bibliographic Details
Main Authors: S. Contreras-Duarte, P. Chen, M. Andía, S. Uribe, P. Irarrázaval, S. Kopp, S. Kern, G. Marsche, D. Busso, C. Wadsack, A. Rigotti
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Biological Research
Subjects:
HDL
Online Access:http://link.springer.com/article/10.1186/s40659-018-0183-6