A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats

A Free-Choice High-Fat High-Sugar Diet Alters Day–Night Per2 Gene Expression in Reward-Related Brain Areas in Rats

Under normal light–dark conditions, nocturnal rodents consume most of their food during the dark period. Diets high in fat and sugar, however, may affect the day–night feeding rhythm resulting in a higher light phase intake. In vitro and in vivo studies showed that nutrients affect clock-gene expres...

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Bibliographic Details
Main Authors: Aurea Susana Blancas-Velazquez, Unga A. Unmehopa, Leslie Eggels, Laura Koekkoek, Andries Kalsbeek, Jorge Mendoza, Susanne E. la Fleur
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Endocrinology
Subjects:
Per2
fat and sugar
clock-genes
obesity
reward
nucleus accumbens
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2018.00154/full

Internet

http://journal.frontiersin.org/article/10.3389/fendo.2018.00154/full

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