Association of the DNMT3B -579G>T polymorphism with risk of thymomas in patients with myasthenia gravis.

Increasing evidence suggests a contribution of epigenetic processes in promoting cancer and autoimmunity. Myasthenia gravis (MG) is an autoimmune disease mediated, in approximately 80% of the patients, by antibodies against the nicotinic acetylcholine receptor (AChR+). Moreover, epithelial tumours (...

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Bibliographic Details
Main Authors: Fabio Coppedè, Roberta Ricciardi, Maria Denaro, Anna De Rosa, Carlo Provenzano, Emanuela Bartoccioni, Angelo Baggiani, Marco Lucchi, Alfredo Mussi, Lucia Migliore
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3834310?pdf=render