A Role for the Androgen Metabolite, 5alpha androstane, 3beta, 17beta Diol (3b-DIol) in the regulation of the hypothalamo-pituitary-adrenal axis.

Activation of the hypothalamo-pituitary-adrenal (HPA) axis is a basic reaction of animals to environmental perturbations that threaten homeostasis. These responses are ultimately regulated by neurons residing within the paraventricular nucleus of the hypothalamus (PVN). Within the PVN, corticotropi...

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Bibliographic Details
Main Authors: Robert James Handa, Dharmendra eSharma, Rosalie M Uht
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2011.00065/full