Collection of cell-free DNA for genomic analysis of solid tumors in a clinical laboratory setting.

The breadth of diagnostic procedures that utilize cell free DNA (cfDNA) from human plasma has increased dramatically in recent years. Here, we confirm that tumor-derived cfDNA fragments are similar in size distribution to cfDNA derived from normal tissues. Therefore, collection procedures optimized...

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Bibliographic Details
Main Authors: Christopher K Raymond, Jennifer Hernandez, Reynold Karr, Kay Hill, Mark Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5407747?pdf=render