Alteration of Synaptic Connectivity of Oligodendrocyte Precursor Cells Following Demyelination

Alteration of Synaptic Connectivity of Oligodendrocyte Precursor Cells Following Demyelination

Oligodendrocyte precursor cells (OPCs) are a major source of remyelinating oligodendrocytes in demyelinating diseases such as multiple sclerosis (MS). While OPCs are innervated by unmyelinated axons in the normal brain, the fate of such synaptic contacts after demyelination is still unclear. By comb...

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Bibliographic Details
Main Authors: Aurélia eSahel, Fernando C. Ortiz, Christophe eKerninon, Paloma P. Maldonado, María Cecilia eAngulo, Brahim eNait-Oumesmar
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Multiple Sclerosis
oligodendrocyte
demyelination
oligodendrocyte precursor cells
NG2 cells
Neuron-OPC synapses
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00077/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00077/full

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