Inferring protein modulation from gene expression data using conditional mutual information.
Systematic, high-throughput dissection of causal post-translational regulatory dependencies, on a genome wide basis, is still one of the great challenges of biology. Due to its complexity, however, only a handful of computational algorithms have been developed for this task. Here we present CINDy (C...
Main Authors: | Federico M Giorgi, Gonzalo Lopez, Jung H Woo, Brygida Bisikirska, Andrea Califano, Mukesh Bansal |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4196905?pdf=render |
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