Alternative Splicing in the Hippo Pathway—Implications for Disease and Potential Therapeutic Targets

Alternative Splicing in the Hippo Pathway—Implications for Disease and Potential Therapeutic Targets

Alternative splicing is a well-studied gene regulatory mechanism that produces biological diversity by allowing the production of multiple protein isoforms from a single gene. An involvement of alternative splicing in the key biological signalling Hippo pathway is emerging and offers new therapeutic...

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Bibliographic Details
Main Authors: Sean Porazinski, Michael Ladomery
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Genes
Subjects:
Hippo pathway
alternative splicing
yes-associated protein
splice-switching oligonucleotides
gene therapy
Online Access:http://www.mdpi.com/2073-4425/9/3/161

Internet

http://www.mdpi.com/2073-4425/9/3/161

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