Thinking outside the Laboratory: Analyses of Antibody Structure and Dynamics within Different Solvent Environments in Molecular Dynamics (MD) Simulations

Thinking outside the Laboratory: Analyses of Antibody Structure and Dynamics within Different Solvent Environments in Molecular Dynamics (MD) Simulations

Monoclonal antibodies (mAbs) have revolutionized the biomedical field, directly influencing therapeutics and diagnostics in the biopharmaceutical industry, while continuing advances in computational efficiency have enabled molecular dynamics (MD) simulations to provide atomistic insight into the str...

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Bibliographic Details
Main Authors: Mohammed M. Al Qaraghuli, Karina Kubiak-Ossowska, Paul A. Mulheran
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Antibodies
Subjects:
implicit solvent
explicit solvent
root-mean-square distance (RMSD)
root-mean-square fluctuations (RMSF)
antibody
molecular dynamics (MD)
Online Access:http://www.mdpi.com/2073-4468/7/3/21

Internet

http://www.mdpi.com/2073-4468/7/3/21

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