PTX3 Intercepts Vascular Inflammation in Systemic Immune-Mediated Diseases

PTX3 Intercepts Vascular Inflammation in Systemic Immune-Mediated Diseases

PTX3 is a prototypic soluble pattern recognition receptor, expressed at sites of inflammation and involved in regulation of the tissue homeostasis. PTX3 systemic levels increase in many (but not all) immune-mediated inflammatory conditions. Research on PTX3 as a biomarker has so far focused on singl...

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Bibliographic Details
Main Authors: Giuseppe A. Ramirez, Patrizia Rovere-Querini, Miriam Blasi, Silvia Sartorelli, Maria Chiara Di Chio, Mattia Baldini, Rebecca De Lorenzo, Enrica P. Bozzolo, Roberto Leone, Alberto Mantovani, Angelo A. Manfredi, Enrico Tombetti
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Immunology
Subjects:
PTX3
autoimmunity
lupus
rheumatoid arthritis
Takayasu arteritis
giant cell arteritis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01135/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01135/full

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