TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.

TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.

Telomerase serves a critical role in stem cell function and tissue homeostasis. This role depends on its ability to synthesize telomere repeats in a manner dependent on the reverse transcriptase (RT) function of its protein component telomerase RT (TERT), as well as on a novel pathway whose mechanis...

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Bibliographic Details
Main Authors: Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah, Stuart K Kim, Steven E Artandi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2211538?pdf=render

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http://europepmc.org/articles/PMC2211538?pdf=render

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