TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.
Telomerase serves a critical role in stem cell function and tissue homeostasis. This role depends on its ability to synthesize telomere repeats in a manner dependent on the reverse transcriptase (RT) function of its protein component telomerase RT (TERT), as well as on a novel pathway whose mechanis...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2008-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2211538?pdf=render |