Enrichment of HLA Types and Single-Nucleotide Polymorphism Associated With Non-progression in a Strictly Defined Cohort of HIV-1 Controllers

Enrichment of HLA Types and Single-Nucleotide Polymorphism Associated With Non-progression in a Strictly Defined Cohort of HIV-1 Controllers

HIV-1 controllers (HIC) are extremely rare patients with the ability to control viral replication, maintain unchanging CD4 T-cell count, and evade disease progression for extensive periods of time, in the absence of antiretroviral therapy. In order to establish the representation of key genetic corr...

Full description

Bibliographic Details
Main Authors: Samantha J. Westrop, Alexander T. H. Cocker, Adriano Boasso, Ann K. Sullivan, Mark R. Nelson, Nesrina Imami
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Immunology
Subjects:
HIV-1
disease progression
elite controllers
HLA antigens
single-nucleotide polymorphism
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00746/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2017.00746/full

Similar Items