CRLF1 Is a Key Regulator in the Ligamentum Flavum Hypertrophy

CRLF1 Is a Key Regulator in the Ligamentum Flavum Hypertrophy

Hypertrophy of the ligamentum flavum (HLF) is one of the common causes of lumbar spinal stenosis (LSS). The key molecules and mechanisms responsible for HLF remain unclear. Here, we used an integrated transcriptome and proteomics analysis of human ligamentum flavum (LF), and subsequent immunohistoch...

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Bibliographic Details
Main Authors: Zhenyu Zheng, Xiang Ao, Peng Li, Zhengnan Lian, Tao Jiang, Zhongmin Zhang, Liang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
ligamentum flavum hypertrophy
CRLF1
fibrosis
proteomics analysis
mouse model
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2020.00858/full

Internet

https://www.frontiersin.org/article/10.3389/fcell.2020.00858/full

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