Aryl Hydrocarbon Receptor Agonist VAF347 Impedes Retinal Pathogenesis in Diabetic Mice

Aryl Hydrocarbon Receptor Agonist VAF347 Impedes Retinal Pathogenesis in Diabetic Mice

Diabetic retinopathy is the leading cause of blindness in the working-age population worldwide. Although the cause of diabetic retinopathy is multifactorial, IL-17A is a prevalent inflammatory cytokine involved in the promotion of diabetes-mediated retinal inflammation and the progression of diabeti...

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Bibliographic Details
Main Authors: Thomas E. Zapadka, Sarah I. Lindstrom, Julia C. Batoki, Chieh A. Lee, Brooklyn E. Taylor, Scott J. Howell, Patricia R. Taylor
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
diabetic retinopathy
AhR
VAF347
retinal inflammation
capillary degeneration
IL-17A
Online Access:https://www.mdpi.com/1422-0067/22/9/4335

Internet

https://www.mdpi.com/1422-0067/22/9/4335

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