Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior
Abstract The 15q13.3 microdeletion syndrome is a genetic disorder characterized by a wide spectrum of psychiatric disorders that is caused by the deletion of a region containing 7 genes on chromosome 15 (MTMR10, FAN1, TRPM1, MIR211, KLF13, OTUD7A, and CHRNA7). The contribution of each gene in this s...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-03-01
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Series: | Molecular Brain |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13041-021-00749-y |