Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior

Mice with mutations in Trpm1, a gene in the locus of 15q13.3 microdeletion syndrome, display pronounced hyperactivity and decreased anxiety-like behavior

Abstract The 15q13.3 microdeletion syndrome is a genetic disorder characterized by a wide spectrum of psychiatric disorders that is caused by the deletion of a region containing 7 genes on chromosome 15 (MTMR10, FAN1, TRPM1, MIR211, KLF13, OTUD7A, and CHRNA7). The contribution of each gene in this s...

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Bibliographic Details
Main Authors: Tesshu Hori, Shohei Ikuta, Satoko Hattori, Keizo Takao, Tsuyoshi Miyakawa, Chieko Koike
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Molecular Brain
Subjects:
15q13.3 microdeletion syndrome
TRPM1
Hyperactivity
ADHD
Visual impairment
Retinal ON bipolar
Online Access:https://doi.org/10.1186/s13041-021-00749-y

Internet

https://doi.org/10.1186/s13041-021-00749-y

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