A MYC-Driven Plasma Polyamine Signature for Early Detection of Ovarian Cancer

A MYC-Driven Plasma Polyamine Signature for Early Detection of Ovarian Cancer

MYC is an oncogenic driver in the pathogenesis of ovarian cancer. We previously demonstrated that MYC regulates polyamine metabolism in triple-negative breast cancer (TNBC) and that a plasma polyamine signature is associated with TNBC development and progression. We hypothesized that a similar plasm...

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Bibliographic Details
Main Authors: Johannes F. Fahrmann, Ehsan Irajizad, Makoto Kobayashi, Jody Vykoukal, Jennifer B. Dennison, Eunice Murage, Ranran Wu, James P. Long, Kim-Anh Do, Joseph Celestino, Karen H. Lu, Zhen Lu, Robert C. Bast, Samir Hanash
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
blood-based biomarkers
polyamines
ovarian cancer
early detection
Online Access:https://www.mdpi.com/2072-6694/13/4/913

Internet

https://www.mdpi.com/2072-6694/13/4/913

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