Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells

Aleuritolic Acid Impaired Autophagic Flux and Induced Apoptosis in Hepatocellular Carcinoma HepG2 Cells

Aleuritolic acid (AA) is a triterpene that is isolated from the root of Croton crassifolius Geisel. In the present study, the cytotoxic effects of AA on hepatocellular carcinoma cells were evaluated. AA exerted dose- and time-dependent cytotoxicity by inducing mitochondria-dependent apoptosis in the...

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Bibliographic Details
Main Authors: Hua Yi, Kun Wang, Biaoyan Du, Lina He, Hiuting HO, Maosong Qiu, Yidan Zou, Qiao Li, Junfeng Jin, Yujuan Zhan, Zhongxiang Zhao, Xiaodong Liu
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Molecules
Subjects:
aleuritolic acid
autophagy
apoptosis
Online Access:http://www.mdpi.com/1420-3049/23/6/1338

Internet

http://www.mdpi.com/1420-3049/23/6/1338

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