Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment

Glioblastoma Recurrence Correlates With Increased APE1 and Polarization Toward an Immuno-Suppressive Microenvironment

While treatment with surgery, radiotherapy and/or chemotherapy may prolong life for patients with glioblastoma, recurrence is inevitable. What is still being discovered is how much these treatments and recurrence of disease affect the molecular profiles of these tumors and how these tumors adapt to...

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Bibliographic Details
Main Authors: Amanda L. Hudson, Nicole R. Parker, Peter Khong, Jonathon F. Parkinson, Trisha Dwight, Rowan J. Ikin, Ying Zhu, Jason Chen, Helen R. Wheeler, Viive M. Howell
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-08-01
Series:Frontiers in Oncology
Subjects:
glioblastoma
recurrence
immuno-suppression
macrophage polarization
microenvironment
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00314/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00314/full

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