DABCO catalyzed rapid one-pot synthesis of 1,4-dihydropyrano [2,3-c] pyrazole derivatives in aqueous media

A simple and efficient protocol is developed for the synthesis of dihydropyrano[2,3-c]pyrazole derivatives by a one pot, four component reaction of ethylacetoacetate, hydrazine hydrate, malanonitrile and various aldehydes in the presence of a catalytic amount of DABCO in aqueous medium. This method...

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Bibliographic Details
Main Authors: Amit S. Waghmare, Shivaji S. Pandit
Format: Article
Published: Elsevier 2017-03-01
Series:Journal of Saudi Chemical Society
Online Access:http://www.sciencedirect.com/science/article/pii/S1319610315000885