Multiclass Classifier for P-Glycoprotein Substrates, Inhibitors, and Non-Active Compounds

Multiclass Classifier for P-Glycoprotein Substrates, Inhibitors, and Non-Active Compounds

P-glycoprotein (P-gp) is a transmembrane protein that actively transports a wide variety of chemically diverse compounds out of the cell. It is highly associated with the ADMET (absorption, distribution, metabolism, excretion and toxicity) properties of drugs/drug candidates and contributes to decre...

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Bibliographic Details
Main Authors: Liadys Mora Lagares, Nikola Minovski, Marjana Novič
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Molecules
Subjects:
P-glycoprotein
counter-propagation artificial neural networks (CP ANN)
multiclass classifier
substrates
inhibitors
Online Access:https://www.mdpi.com/1420-3049/24/10/2006

Internet

https://www.mdpi.com/1420-3049/24/10/2006

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